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Article Outline

  1. Preface: Onwards and upwards, xv
  2. Psychotherapeutics
    1. Advances in Psychotherapy for Posttraumatic Stress Disorder, 1
  3. Advances in Psychotherapy for Eating Disorders, 13
  4. Is Less Really More? Analysis of Brief, Intensive Treatments for Obsessive-Compulsive Disorder, 25
  5. Third-Wave Cognitive Behavioral Therapy for Obsessive Compulsive Disorder?: A Promising Approach if It Includes Exposure, 37
  6. Suicide Research
    1. Digital Technology for Suicide Prevention, 53
  7. Identifying People at Risk for Suicide: Implementation of Screening for the Zero Suicide Initiative in Large Health Systems, 67
  8. Lethal Means Safety Approaches for Suicide Prevention, 77
  9. Women's Mental Health
    1. Treatment of Premenstrual Dysphoric Disorder (PMDD): Advances and Challenges, 91
  10. Novel Neurosteroid Pharmaceuticals: Implications Across a Woman's Lifecycle, 107
  11. Sports Psychiatry
    1. Mental Health in Youth Athletes: A Clinical Review, 119
  12. Diagnosis and Management of Substance Use Disorders in Athletes, 135
  13. Sex Differences in Psychiatric Diagnosis and Management of Athletes, 145
  14. Anxiety Disorders in Athletes: A Clinical Review, 149
  15. Neurosciences
    1. Neuropsychiatric Manifestations of COVID-19: A Review, 161
  16. The Use of Repetitive Transcranial Magnetic Stimulation in Depression and Other Psychiatric Disorders; the Knowns and the Unknowns, 173
  17. Advances in Depression Management: Multifunctional Antidepressant Medications, 185
  18. Education
    1. Dementia After Traumatic Brain Injury: From Neural Mechanisms to Psychiatry, 205
  19. Learning Psychiatry: Then and Now, 219
  20. Clinical Psychology Training: Past, Present, and Future, 229
  21. Integrating Book Club in Psychiatric Education, 239

Editorial Board, iii

Contributors, v

Preface: Onwards and upwards, xv

By Deepak Prabhakar

Psychotherapeutics

Advances in Psychotherapy for Posttraumatic Stress Disorder, 1

By Alison Krauss, Ena Begovic, Kristina Harper, and Ellen J. Teng

 Introduction,  1

 Overview of evidence-based treatments for posttraumatic stress disorder,  2

Prolonged Exposure Therapy,  2

Cognitive Processing Therapy,  2

Eye Movement Desensitization and Reprocessing,  4

Cognitive Behavioral Therapy,  4

Brief Eclectic Psychotherapy for Posttraumatic Stress Disorder,  4

Narrative Exposure Therapy,  5

 Intensive and brief posttraumatic stress disorder treatment approaches,  5

Intensive Trauma-Focused Treatments,  5

Brief Treatments,  5

 Technology-assisted delivery of posttraumatic stress disorder treatment,  6

Internet-Based Interventions,  6

Mobile Applications,  6

Video Telehealth,  7

 Practice considerations,  7

 Clinics care points,  8

Advances in Psychotherapy for Eating Disorders, 13

By Cody Staples, William Grunewald, April R. Smith, and Diana Rancourt

 Background,  13

 Current evidence,  13

Psychotherapy for Anorexia Nervosa,  14

Psychotherapy for Bulimia Nervosa,  14

Psychotherapy for Binge Eating Disorder,  15

Psychotherapy for Avoidant/Restrictive Food Intake Disorder,  16

Factors Predicting Treatment Outcomes,  16

Telehealth, Online Interventions, and Just-in-Time-Adaptive Interventions,  16

 Other Promising Approaches,  17

Cue exposure and response prevention,  17

Appetite awareness training,  17

Biofeedback-focused approaches,  17

Unified protocol,  17

 Understudied Populations,  17

 Discussion,  18

 Summary,  19

 Clinics care points,  19

Is Less Really More? Analysis of Brief, Intensive Treatments for Obsessive-Compulsive Disorder, 25

By Bradley C. Riemann, Sarah J. David, Nicholas R. Farrell, and Brenda E. Bailey

 Exposure-based treatment for obsessive-compulsive disorder: massed versus spaced models,  26

 Brief intensive treatments for pediatric obsessive-compulsive disorder,  27

 Brief intensive treatment for adult obsessive-compulsive disorder,  28

 Strength of data,  30

 Theoretic basis for findings of brief exposure and response prevention models,  31

 Summary and future directions in brief, intensive treatments for obsessive-compulsive disorder,  32

 Disclosure,  33

Third-Wave Cognitive Behavioral Therapy for Obsessive Compulsive Disorder?: A Promising Approach if It Includes Exposure, 37

By Erika S. Trent, Andrew G. Guzick, Andres G. Viana, and Eric A. Storch

 Introduction/background,  37

 Rationale,  38

 Approach,  39

 Current evidence,  39

Acceptance and Commitment Therapy,  39

Mindfulness-Based Therapies,  45

Metacognitive Therapy,  46

 Discussion,  47

Recommendations,  47

Future Directions,  48

 Summary,  48

 Clinics care points,  48

 Disclosure,  48

Suicide Research

Digital Technology for Suicide Prevention, 53

By Jordan M. Braciszewski

 Introduction,  53

Gaps in Current Approaches to Identification and Treatment,  53

Leveraging Digital Technologies to Address a Major Public Health Problem,  54

 Current evidence,  55

Technology-Based Screening,  55

Self-Guided Internet-Based Approaches,  55

Mobile Applications,  55

Data-Driven Approaches to Identification,  57

 Adoption of digital strategies,  57

 Future directions,  58

 Summary and recommendations for practitioners,  59

 Clinics care points,  60

 Disclosure,  60

Identifying People at Risk for Suicide: Implementation of Screening for the Zero Suicide Initiative in Large Health Systems, 67

By Karen J. Coleman, Christine C. Stewart, Cambria Bruschke, Jean P. Flores, Andrea Altschuler, Arne Beck, Frances L. Lynch, Ashli A. Owen-Smith, Julie E. Richards, Rebecca Rossom, Gregory E. Simon, Stacy Sterling, and Brian K. Ahmedani

 Introduction,  68

 Methods,  69

Study Design,  69

Settings and Population,  69

Zero Suicide Care Improvements,  69

Data and Sources for Evaluation,  70

 Analyses,  70

 Results,  70

 Discussion,  72

Considerations for Implementation,  73

Limitations,  73

Future Directions,  74

 Clinics care points,  74

 Disclosure,  74

Lethal Means Safety Approaches for Suicide Prevention, 77

By Leslie Barnard, Ali Rowhani-Rahbar, and Marian E. Betz

 Background,  77

 Framework for prevention efforts,  78

Societal,  78

Community,  80

Relationship,  81

Individual,  82

 Challenges for lethal means safety approaches,  83

 Future directions,  84

 Summary,  85

 Clinics care points,  85

 Disclosure,  85

Women's Mental Health

Treatment of Premenstrual Dysphoric Disorder (PMDD): Advances and Challenges, 91

By Liisa Hantsoo and Julia Riddle

 Introduction,  91

Diagnosis Informs Treatment,  91

 Premenstrual dysphoric disorder treatment,  92

Selective Serotonin Reuptake Inhibitors,  92

Hormonal Contraceptives,  93

Psychotherapy,  93

Gonadotropin-Releasing Hormone Medications,  93

Surgical Oophorectomy,  94

 Treatment challenges,  94

Medication Nonresponse,  94

Comorbidities,  94

Reproductive Transitions,  100

 Recent developments in treatment,  100

Neuroactive Steroid-Based Pharmacotherapy,  100

Internet-Based Cognitive-Behavioral Therapy,  101

 Discussion,  101

 Summary,  101

 Clinics care points,  101

 Disclosure,  102

Novel Neurosteroid Pharmaceuticals: Implications Across a Woman's Lifecycle, 107

By Leah C. Susser, Clare Swanson, and Alison D. Hermann

 Introduction,  107

 Background,  107

 Perinatal depression,  108

Brexanolone,  108

Zuranolone (SAGE-217),  112

Ganaxolone,  112

SGE-516,  112

 Premenstrual dysphoric disorder,  113

Dutasteride,  113

Sepranolone,  113

Ulipristal acetate (UPA),  114

 Perimenopausal depression,  114

 Other periods of a woman’s life,  114

 Limitations and future directions for reproductive depression treatment with neuroactive steroids,  114

 Summary,  115

 Clinics care points,  115

 Disclosure,  115

Sports Psychiatry

Mental Health in Youth Athletes: A Clinical Review, 119

By Courtney C. Walton, Simon Rice, R.I. (Vana) Hutter, Alan Currie, Claudia L. Reardon, and Rosemary Purcell

 Introduction,  119

 Young people can thrive through sport,  120

 Mental health and related stressors in youth sport,  120

Pressure to Perform and Perfectionism,  120

Burnout and Early Specialization,  123

Peer and Parental Conflict,  123

Abuse and Maltreatment,  123

Injury and Concussion,  124

Body Image and Weight Concerns,  124

Disrupted Sleep,  124

 Assessment of youth athletes,  125

Athlete Resistance and Mental Health Stigma,  125

Assessment Tools,  125

Collateral Information,  126

 Treatment of youth athletes,  126

Psychological Approaches,  126

Pharmacologic Considerations,  126

 Summary,  129

 Disclosure,  129

Diagnosis and Management of Substance Use Disorders in Athletes, 135

By Pamela Walters, Bradley Hillier, Filippo Passetti, Anju Soni, and Ian Treasaden

 Introduction,  135

 Background,  135

Neurobiological Correlates: Athletes and Addictive Behaviors,  136

Diagnostic Criteria for Substance Use Disorder,  136

Assessment,  136

 Pharmacologic interventions,  136

Background,  136

Alcohol,  136

Cannabis,  140

Nicotine,  140

Stimulants,  140

Opioids,  141

Psychosocial Interventions,  141

 Summary,  141

 Disclosure,  142

Sex Differences in Psychiatric Diagnosis and Management of Athletes, 145

By Danielle Kamis

 Sex differences in psychopathology,  145

Mood Disorders,  145

Anxiety Disorders,  145

The Female Athletic Triad,  145

Eating Disorders,  146

Substance Use,  146

Clinical Case,  147

 Summary and future direction,  147

 Disclosure,  147

Anxiety Disorders in Athletes: A Clinical Review, 149

By Claudia L. Reardon, Paul Gorczynski, Brian Hainline, Mary Hitchcock, Rosemary Purcell, Simon Rice, and Courtney Walton

 Introduction/background,  149

 General information,  150

 Generalized anxiety disorder,  150

 Panic disorder,  150

 Social anxiety disorder,  151

 Obsessive-compulsive disorder,  151

 Competitive performance anxiety,  152

 Other anxiety-related disorders,  153

 General principles of diagnosis and management,  153

 Discussion,  156

 Summary,  157

 Clinics care points,  157

 Disclosure,  157

Neurosciences

Neuropsychiatric Manifestations of COVID-19: A Review, 161

By Moein Foroughi, Rishab Gupta, Amvrine Ganguly, Junaid Mirza, and Aryandokht Fotros

 Introduction,  161

 Methods,  162

 COVID-19 and delirium,  162

 COVID-19 and cognitive deficits,  163

 COVID-19 and psychosis,  163

 COVID-19 and depression,  164

 COVID-19 and suicide,  164

 COVID-19 and mania,  165

 COVID-19 and anxiety,  165

 Proposed neurobiological mechanisms,  166

 Neuropsychiatric adverse effects of medications used to treat COVID-19,  166

 Psychosocial factors associated with COVID-19 as risk factors for neuropsychiatric disorders,  167

 Discussion,  167

 Disclosure,  169

The Use of Repetitive Transcranial Magnetic Stimulation in Depression and Other Psychiatric Disorders; the Knowns and the Unknowns, 173

By Mandana Modirrousta, Benjamin P. Meek, and Mohamed Abo Aoun

 Introduction,  173

 Patient factors,  174

 Disease factors,  175

 Treatment-specific factors,  175

Frequency,  175

Number of Pulses,  175

Stimulation Intensity,  176

Stimulation Target,  176

Duration of Treatment,  177

Side Effects,  177

Pre-TMS Evaluation,  177

 rTMS in other psychiatric disorders,  178

Obsessive Compulsive Disorder (OCD),  178

Schizophrenia,  178

Substance Use Disorder,  178

Eating Disorders,  178

Anxiety Disorders,  178

Posttraumatic Stress Disorder (PTSD),  178

 Summary,  178

 Clinics care points,  179

 Disclosure,  179

Advances in Depression Management: Multifunctional Antidepressant Medications, 185

By Michael Ingram, Gerald Maguire, and Stephen M. Stahl

 Introduction,  185

Multifunctional antidepressant mechanisms,  186

Monoamine reuptake inhibition,  186

Combining types of monoamine reuptake inhibition for multifunctional treatment of depression,  186

Combining norepinephrine and dopamine reuptake inhibition,  189

Combining serotonin reuptake inhibition with agonist or antagonist actions at multiple serotonin receptor subtypes,  192

Combining serotonin reuptake inhibition with serotonin receptor antagonism,  195

Norepinephrine antagonism and mirtazapine,  199

Should a combination of antidepressant mechanisms be the standard for treating unipolar depression?,  200

 Summary,  202

 Disclosures,  202

Education

Dementia After Traumatic Brain Injury: From Neural Mechanisms to Psychiatry, 205

By Vassilis E. Koliatsos, Vani Rao, and Athanasios S. Alexandris

 The problem and its significance,  205

 The typology of chronic traumatic brain injury,  206

Traumatic Brain Injury: Transient Versus Chronic Disease,  206

Focal Contusions,  207

Acceleration Injuries: Diffuse Axonal Injury,  207

Repetitive Mild Traumatic Brain Injury and Chronic Traumatic Encephalopathy,  207

Blast Injury to Brain,  208

 Select mechanisms of degeneration after traumatic brain injury,  208

Traumatic Axonopathy and Disconnection—the Importance of the White Matter,  208

Protein Aggregation (Proteinopathy),  209

 Chronic traumatic brain injury as neuropsychiatric disease,  209

Clinical Presentations,  209

Brain-Behavior Correlations,  210

 Cognitive impairments and dementia after traumatic brain injury,  211

Overview,  211

Neurodegenerative Disease Specific to Traumatic Brain Injury: the Problem of Athletic Concussions and Chronic Traumatic Encephalopathy,  212

Traumatic Brain Injury as a Risk Factor for Neurodegeneration Other Than Chronic Traumatic Encephalopathy,  214

 Summary,  214

Learning Psychiatry: Then and Now, 219

By Lisa MacLean and Deepak Prabhakar

 Introduction,  219

 Discussion,  220

Training Attitudes,  220

Culture of Medicine,  221

Assessment of Clinician Well-Being,  222

Advances in Technology,  222

Supervision Challenges,  223

The Current and Future Practice of Psychiatry,  223

 Summary,  226

 Disclosure,  226

Clinical Psychology Training: Past, Present, and Future, 229

By Lisa R. Miller-Matero, Nora Coultis, Anissa J. Maffett, Brittany A. Haage, Sai B. Narotam, and Kellie M. Martens

 Introduction,  229

 Specialties and board certification,  229

Training in Specialties and Board Certification,  230

Future Directions,  231

 Integrated care,  231

Training in Integrated Care,  231

Future Directions,  232

 Technology,  232

Training in Technology,  232

Future Directions,  232

 Multiculturalism,  233

Training in Multicultural Considerations,  233

Future Directions,  234

 Summary,  234

 Disclosure,  234

Integrating Book Club in Psychiatric Education, 239

By Deepak Prabhakar and Lisa MacLean

 Introduction,  239

 Background,  240

 Book club design,  240

 Other considerations,  242

 Book descriptions and session details,  242

 Summary,  243

 Clinics care points,  244

 Disclosure,  244

 

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