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Infertility is a complex medical phenomenon with the potential for profound impact on mental health. The relationship between infertility and mental health is bidirectional, with interactions in pathophysiology and treatment. Evidence suggests that depression, anxiety, and emotional distress are more prevalent in those undergoing infertility evaluation and assisted reproductive technology, and that the presence of these mental health conditions may have an impact on the outcomes of evaluation and treatment. Evidence-based treatment approaches in the context of infertility are often administered by infertility centers directly. Screening and referral for appropriate treatment can improve outcomes for patients with infertility.

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